Edwin P. Alcantara – National Institute of Molecular Biology and Biotechnology
Biotech University of the Philippines (Los Banos) College, Laguna 4031 Philippines
Introduction: A pharmacophore is the set of chemical and steric interactions between a ligand and macromolecule that are relevant to trigger biological response. In this study, the enzyme β-N-acetyl-D-hexosaminidase (PDB I.D. 3NSN) was used as model macromolecule because 3NSN is involved in chitin degradation during pupation in the Asian corn borer Ostrinia furnacalis
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